Playa poses no great dangers, but take the usual precautions. Don't leave valuables unattended or leave them visible in a parked rental car. And you may want to resist the temptation to seek out a totally secluded section of shoreline: You're safer in places where you can see others. Likewise, avoid walking on the beach at night unless there are other people present and the area is well-lit. It's best not to stray too deep into town, particularly after nightfall. The Colosio neighborhood on the north edge of town is known to be a bit rough-and-tumble.
For the latest information, contact your country's travel-advisory agency.
The water is usually safe in the major hotels and restaurants serving tourists, but ask to make sure it is
agua purificada (purified water). Bottled water is also widely available. Be careful also with drinks that are frozen or served on the rocks: They can spell trouble if the ice wasn't made with purified water. Stick to the tourist hotels and restaurants for food—do not eat anything from street vendors. Take along a sufficient supply of any medications you require: No pharmacy will fill a prescription for a controlled substance unless it is written in Spanish by a physician licensed in Mexico. Ask your doctor about hepatitis vaccinations before you leave on your trip. In case of an emergency, there is a hospital at the corner of avenidas 15 and Juarez.
For the latest information, contact your country's health-advisory agency.
Avenida 5 is fairly accessible, with most shops, restaurants and bars offering stair-free access. The larger hotels are wheelchair accessible, but many of the smaller hotels are not. Outside of Avenida 5, the roads do not offer much in the way of ramps or smooth surfaces, making access difficult.
Do wear sunscreen. The tropical sun is especially harsh in the early afternoon, and serious burns can occur in less than an hour.
Do drink plenty of water. The body dehydrates quickly in the tropical climate and can lead to headaches, nausea and tiredness.
Don't assume passing vehicles will stop at crosswalks. Traffic around the touristy areas can be heavy, so be careful when crossing the street.
Don't sunbathe nude or topless (women) in areas frequented by locals.
Do try some local foods, such as the whole fried fish, shrimp seviche or enchiladas with mole sauce.